Cephalic phase, reflex insulin secretion neuroanatomical and physiological characterization
نویسندگان
چکیده
منابع مشابه
Cephalic phase secretion of insulin and other enteropancreatic hormones in humans.
Enteropancreatic hormone secretion is thought to include a cephalic phase, but the evidence in humans is ambiguous. We studied vagally induced gut hormone responses with and without muscarinic blockade in 10 glucose-clamped healthy men (age: 24.5 ± 0.6 yr, means ± SE; body mass index: 24.0 ± 0.5 kg/m(2); HbA1c: 5.1 ± 0.1%/31.4 ± 0.5 mmol/mol). Cephalic activation was elicited by modified sham f...
متن کاملAnticipatory physiological regulation in feeding biology: cephalic phase responses.
Anticipatory physiological regulation is an adaptive strategy that enables animals to respond faster to physiologic and metabolic challenges. The cephalic phase responses are anticipatory responses that prepare animals to digest, absorb, and metabolize nutrients. They enable the sensory aspects of the food to interact with the metabolic state of the animal to influence feeding behavior. The ant...
متن کاملCephalic phase insulin release in healthy humans after taste stimulation?
In humans little is known as to whether taste solutions applied to the tongue elicit cephalic phase insulin release (CPIR). The aim of this study was to re-examine if any effect of different taste solutions on CPIR occurs. Under fasting conditions healthy human subjects sipped, and washed out their mouths with eight taste solutions (sucrose, saccharin, acetic acid, sodium chloride, quinine hydr...
متن کاملCephalic phase of insulin secretion in response to a meal is unrelated to family history of type 2 diabetes
The pre-absorptive cephalic phase of insulin secretion is elicited during the first ten min of a meal and before glucose levels rise. Its importance for insulin release during the post-absorptive phase has been well documented in animals but its presence or importance in man has become increasingly controversial. We here examined the presence of an early cephalic phase of insulin release in 31 ...
متن کاملSecond-phase insulin secretion gets cool.
STIMULUS-SECRETION COUPLING of insulin is a highly orchestrated process initiated by the uptake of glucose by pancreatic -cells culminating with the fusion of insulin vesicles with the plasma membrane and release of insulin into the extracellular space. A hallmark feature of stimulus-secretion coupling is the biphasic nature of insulin secretion following an elevation in plasma glucose levels (...
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ژورنال
عنوان ژورنال: Diabetologia
سال: 1981
ISSN: 0012-186X,1432-0428
DOI: 10.1007/bf00254508